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EGF Protein, Rat

EGF Protein, Rat

货号: UA040228
价格: 580
规格: 10μg
介绍: -
其他: -
产品规格

  • 物种

    Rat

  • 分子别名

    Pro-epidermal growth factor, Epidermal growth factor, EGF

  • Accession

    P07522

  • 表达序列

    N974-R1026

  • 表达宿主

    E.coli

  • 分子量

    6kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 活性

    <0.1ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM PB, 100mM NaCl, pH6.0

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Int J Pancreatol. 1992 Aug;12(1):23-9.
    2.Cell Biol Int. 1995 May;19(5):413-30.
    3.J Cell Biochem. 1986;31(2):135-52.

  • 稀释度

背景介绍

  • Epidermal growth factor (EGF) has been localized in human salivary and Brunner's glands and found to stimulate the proliferation of gastrointestinal and pancreatic tissues in animals, is a single polypeptide of 53 amino acid residues which is involved in the regulation of cell proliferation. EGF exerts its effects in the target cells by binding to the plasma membrane located EGF receptor. And The EGF receptor is a transmembrane protein tyrosine kinase. EGF is also a peptide which effects the growth and/or differentiated functions of many cell types. Several pieces of evidence indicate that EGF and its receptor may play a role in carcinogenesis.

  • 生物活性JSON

    • Measured in a cell proliferation assay using Balb/c 3T3 mouse fibroblast cells. The EC50 for this effect is less than 0.1ng/ml.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).