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Biotinylated ICAM-1/CD54 His&Avi Tag Protein, Mouse

货号: UA010889

价格: 2780

规格: 25μg

介绍: -

其他: -

产品规格

物种

Mouse
分子别名

BB2, ICAM1, CD54, P3.58
Accession

P13597-1
表达序列

Gln28-Asn485, with C-terminal His and Avitag
表达宿主

HEK293
分子量

72-90kDa (Reducing)
纯度

＞95% by SDS-PAGE
内毒素含量

<1EU/μg
性状

Lyophilized Powder
缓冲体系

PBS, pH7.4.
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

1. Theresa N. Ramos; Daniel C. Bullard; Scott R. Barnum:ICAM-1: Isoforms and Phenotypes, J Immunol (2014) 192 (10): 4469–4474.

背景介绍

ICAM-1 is a cell surface glycoprotein expressed at a low basal level in immune, endothelial (EC) and epithelial cells, but is up-regulated in response to inflammatory stimulation. The function of ICAM-1 has been best studied in leukocyte transendothelial migration (TEM), where ICAM-1 regulates leukocyte rolling and adhesive interactions with the vessel wall, and guides leukocyte crossing of the endothelial layer. More recently, functional studies identified several new roles of ICAM-1 in epithelial injury-resolution responses, innate and adaptive immune responses in inflammation, and tumorigenesis.