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IL-6 Protein, Canine

IL-6 Protein, Canine

货号: UA040205
价格: 1780
规格: 10μg
介绍: -
其他: -
产品规格

  • 物种

    Canine

  • 分子别名

    Interleukin-6, IL-6;Interleukin-6, IL-6, B-Cell Hybridoma Growth Factor, Interleukin HP-1, Il6, Il-6；

  • Accession

    P41323

  • 表达序列

    Phe21-Met207

  • 表达宿主

    E.coli

  • 分子量

    24kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM Tris,80mM NaCl,pH8.0.

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Ferguson-Smith AC, Chen YF, Newman MS, et al. 1988. Genomics. 2:203-8. 

    2.van der Poll T, Keogh CV, Guirao X, et al. 1997. J Infect Dis. 176:439-44. 

    3.Ming JE, Cernetti C, Steinman RM, et al. 1989. J Mol Cell Immunol. 4:203-11; discussion 211-2. 

    4.Bastard JP, Jardel C, Delattre J, et al. 1999. Circulation. 99:2221-2. 

    5.Heinrich PC, Behrmann I, Muller-Newen G, et al. 1998. Biochem J. 334 ( Pt 2):297-314. 

    6.Van Snick J, Cayphas S, Szikora JP, et al. 1988. Eur J Immunol. 18:193-7.

  • 稀释度

背景介绍

  • Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants.

  • 生物活性JSON

    • Measured by cytotoxicity assay using TF-1 cells. The EC50 for this effect is less than 20ng/ml.

  • 电泳JSON

    • 1μg (R: reducing condition, N: non-reducing condition).