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Human Kim-1 , His tag

Human Kim-1 , His tag

货号: S0A5003
价格: 600
规格: 25μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • 分子别名

    Kidney injury molecule 1, T-cell immunoglobulin and mucin domain-containing protein 1 (TIMD-1), T-cell immunoglobulin mucin receptor 1 (TIM; TIM-1), T-cell membrane protein 1, CD365, HAVCR1
  • Accession

    Q96D42
  • 表达序列

    Protein sequence(Q96D42, Ser21-Gly295, with C-10*His) SVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTTDGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGGGGGSHHHHHHHHHH

  • 表达宿主

    HEK293
  • 分子量

    Theoretical:31.1kDa Actual: 39, 75-110kDa
  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg
  • 标记

    Unconjugated
  • 标签

    His Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍
  • KIM-1 (Kidney Injury Molecule -1) is a protein the most highly upregulated in injured kidneys by various types of insults. Its upregulation during renal injury has been found in the kidneys of the vertebrates such as Zebrafish and humans. A soluble form of human KIM-1 can be detected in the urine of patients with ATN and may serve as a useful biomarker for renal proximal tubule injury facilitating the early diagnosis of the disease and serving as a diagnostic discriminator.

  • 生物活性JSON

    • Immobilized Human Kim-1, His tag at 2 μg/mL (50 μL/well) can bind KIM-1 Recombinant Rabbit mAb (S-932-2) (Cat. No. S0B0604) with EC50 of 3.341-4.967 ng/ ml.

  • 电泳JSON

    • 2μg(R: reducing conditions)