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SARS-CoV-2 (KP.2/Omicron) RBD Protein, His tag

SARS-CoV-2 (KP.2/Omicron) RBD Protein, His tag

货号: S0A2076
价格: 900
规格: 25μg
介绍: -
其他: -
产品规格
  • 物种

    SARS-CoV-2
  • 分子别名

    Spike glycoprotein, S glycoprotein, E2, Peplomer protein
  • Accession

    P0DTC2
  • 表达序列

    Protein sequence (P0DTC2, Arg319-Lys537, with C-His tag) RVQPTESIVRFPNVTNLCPFHEVFNATRFASVYAWNRTRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIKGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKHSGNYDYWYRSLRKSKLKPFERDISTEIYQAGNKPCKGKGPNCYFPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNK

  • 表达宿主

    HEK293
  • 分子量

    Predicted MW: 26.4 kDa Observed MW: 35-40 kDa

  • 纯度

    >90% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 标记

    Unconjugated
  • 标签

    with C-His tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍
  • KP.2 strain, a descendant of the highly contagious JN.1 variant. KP.2 is one of several variants being referred to as “FLiRT variants,” named after the technical names for their mutations. They are characterized by a phenylalanine (F) to leucine (L) mutation and an arginine (R) to threonine (T) mutation in the virus's spike protein. Sars-cov-2 infects human respiratory epithelial cells through binding to human ACE2 receptors. Spike protein is a large type I transmembrane protein containing two subunits S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing cell surface receptors. S2 contains the basic elements required for membrane fusion. S protein plays a key role in inducing neutralizing antibody and T cell responses as well as protective immunity.

  • 生物活性JSON

    • Immobilized SARS-CoV-2 (KP.2/Omicron) RBD Protein, His tag at 4 μg/mL (50 μL/well) can bind Human ACE2, hFc tag (Cat. No. S0A0071) with EC50 of 31.52-35.11 ng/ml.

  • 电泳JSON

    • 2 μg(R: reducing conditions)