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Glycophorin C Recombinant Rabbit mAb (S-027-214)

Glycophorin C Recombinant Rabbit mAb (S-027-214)

货号: S0B0642
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 分子别名

    Glycoconnectin, Glycophorin-D (GPD), Glycoprotein beta, PAS-2', Sialoglycoprotein D, CD236, GYPC
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Cell membrane
  • Accession

    P04921
  • 克隆号

    S-027-214
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    IHC-P
  • 反应种属 ?

    Hu, Ms, Rt
  • 纯化方式

    Protein A
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度
IHC-P 1:500
背景介绍
  • Glycophorin C (GYPC), also known as Gerbich blood group antigen, is a minor sialic acid glycoprotein found in the human erythrocyte membrane. It plays a crucial role in maintaining erythrocyte stability and morphology, located on and integrated into the plasma membrane of red blood cells. The extracellular domain of GYPC may contain Gerbich antigens and receptors for Plasmodium falciparum merozoites. Beyond its role as a blood group determinant, GYPC strictly regulates the structural integrity of erythrocytes and immune interactions. In the medical field, variations or dysfunctions in GYPC may be associated with blood types, the Gerbich blood group, and malaria resistance. Therefore, research on Glycophorin C not only contributes to understanding erythrocyte physiology and blood group genetics but also provides new insights into the prevention and treatment of diseases like malaria.

  • 免疫组化

    • IHC shows positive staining in paraffin-embedded human colon. Anti-Glycophorin C antibody was used at 1/500 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human spleen. Anti-Glycophorin C antibody was used at 1/500 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human placenta. Anti-Glycophorin C antibody was used at 1/500 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human hepatocellular carcinoma. Anti-Glycophorin C antibody was used at 1/500 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human ovarian carcinoma. Anti-Glycophorin C antibody was used at 1/500 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human thyroid carcinoma. Anti-Glycophorin C antibody was used at 1/500 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded mouse kidney. Anti-Glycophorin C antibody was used at 1/500 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded rat lung. Anti-Glycophorin C antibody was used at 1/500 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.