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Rabbit IgM, His tag

Rabbit IgM, His tag

货号: S0A0105
价格: 1350
规格: 25μg
介绍: -
其他: -
产品规格
  • 物种

    Rabbit
  • 分子别名

    Ig mu chain C region secreted form
  • Accession

    P03988-1
  • 表达序列

    Protein sequence (P03988-1, Val107-Tyr458, with C-His tag) VDSELPPNVSVFIPPRDSFSGSGTRKSRLICQATGFSPKQISVSWLRDGQKVESGVLTKPVEAETKGAGPATFSISSMLTITESDWLSQSLYTCRVDHRGIFFDKNVSMSSECSTTPSPGIQVFPIAPSFADTFLSKSARLICLVTDLTTYGSLNISWASHNGKALDTHMNITESHPNATFSAMGEASVCAEDWESGEQFTCTVTHADLPFPLKHTISKSREVAKHPPAVYVLPPAREQLVLRESATVTCLVKGFSPADVFVQWQQRGQPLSSDKYVTSAPAPEPQAPGLYFTHSTLTVTEEDWNSGETFTCVVGHEALPHMVTERTVDKSTGKPTLYNVSLIMSDTASTCY

  • 表达宿主

    HEK293
  • 分子量

    Predicted MW: 39.9 kDa Observed MW: 50-65 kDa
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 标签

    with C-His tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍
  • Immunoglobulin M (IgM) is one of several isotypes of antibody (also known as immunoglobulin) that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. IgM is the first immunoglobulin expressed in the human fetus (around 20 weeks) and phylogenetically the earliest antibody to develop. IgM antibodies do not pass across the human placenta (only isotype IgG). Demonstrating IgM antibodies in a patient's serum indicates recent infection, or in a neonate's serum indicates intrauterine infection (e.g. congenital rubella syndrome). IgM in normal serum is often found to bind to specific antigens, even in the absence of prior immunization. A mutation of the mu chain within IgM causes autosomal recessive agammaglobulinemia. The presence of IgM or, rarely, IgG is one of the obligate criteria for a diagnosis of Schnitzler's syndrome.

  • 电泳JSON

    • 2 μg(R: reducing conditions)