您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
Ctip2 Recombinant Rabbit mAb (S-R314)

Ctip2 Recombinant Rabbit mAb (S-R314)

货号: S0B0456
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    Ctip2
  • 分子别名

    BCL11B, Ctip2, RIT1
  • 细胞定位

    Nucleus
  • Accession

    Q9C0K0
  • 克隆号

    S-R314
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    WB
  • 反应种属 ?

    Hu
  • 纯化方式

    Protein A
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度
WB 1:1000
背景介绍
  • CTIP2 (also known as BCL11B) is a transcription factor Highly expressed in brain and in malignant T-cell lines derived from patients with adult T-cell leukemia/lymphoma. CTIP2 deficiency results in structural striatal defects, impaired spatial learning, and working memory deficits in mice. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Diseases associated with CTIP2 include Immunodeficiency and Intellectual Developmental Disorder with Speech Delay, Dysmorphic Facies, And T-Cell Abnormalities. Among its related pathways are NF-kappaB Signaling and Development and heterogeneity of the ILC family.

  • 免疫印迹

    • WB result of Ctip2 Rabbit mAb
      Primary antibody: Ctip2 Rabbit mAb at 1/1000 dilution
      Lane 1: MOLT-4 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 96 kDa
      Observed MW: 115, 125 kDa