您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
Bevacizumab

Bevacizumab

货号: S0B0437
价格: 1550
规格: 1mg
介绍: -
其他: -
产品规格
  • 宿主来源

    Human
  • 抗原名称

    VEGF
  • 分子别名

    Vascular endothelial growth factor A long form, L-VEGF, Vascular permeability factor (VPF), VEGFA
  • 细胞定位

    Secreted
  • Accession

    P15692
  • 克隆号

    S-SC020
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG1,k
  • 应用

    Blocking of VEGF signaling Functional assays
  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 内毒素含量

    <1EU/mg
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, containing no preservative
  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度
ELISA 1.221-5000 ng/ml
背景介绍
  • Bevacizumab works by blocking a protein called VEGF, which some cancer cells produce in large amounts. Blocking VEGF may prevent the growth of new blood vessels that tumors need to grow. Bevacizumab is a type of targeted therapy called an angiogenesis inhibitor. For cancer, it is given by slow injection into a vein (intravenous) and used for colon cancer, lung cancer, glioblastoma, and renal-cell carcinoma. In many of these diseases it is used as a first-line therapy. For age-related macular degeneration it is given by injection into the eye (intravitreal).

  • ELISA

    • Immobilized human VEGF at 0.5 μg/ml (50μL/well) can bind to Bevacizumab with a linear range of 1.221 ng/ml to 5 μg/ml.