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Langerin Recombinant Rabbit mAb (SDT-450-47)

Langerin Recombinant Rabbit mAb (SDT-450-47)

货号: S0B2278
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    Langerin
  • 分子别名

    C-type lectin domain family 4 member K, CD207, CLEC4K
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Membrane
  • Accession

    Q9UJ71
  • 克隆号

    SDT-450-47
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    IHC-P
  • 反应种属 ?

    Hu
  • 纯化方式

    Protein A
  • 浓度

    0.25 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度
IHC-P 1:1000
背景介绍
  • Langerin (CD207) is a type II transmembrane C-type lectin which is encoded by the CD207 gene in humans. Langerin is known to be associated with the formation of Birbeck granules in Langerhans cells (LCs). LCs are immune cells closely related to macrophages, but by their function, they are more like conventional dendritic cells (cDCs). Langerin is a highly selective marker for Langerhans cells and the lesional cells of Langerhans cell histiocytosis.

  • 免疫组化

    • IHC shows positive staining in paraffin-embedded human esophagus. Anti-Langerin antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human skin. Anti-Langerin antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • Negative control: IHC shows negative staining in paraffin-embedded human cerebral cortex. Anti-Langerin antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.