PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Hu, Ms, Rt |
IKKβ, also known as IκB kinase β or IKK2, is a key regulatory kinase responsible for the activation of NF-κB through phosphorylation at specific serine residues. It is a crucial component of the IKK complex, which includes IKKα, IKKβ, and the regulatory subunit IKKγ (NEMO). Dysregulation of IKKβ activity has been implicated in several cancer types, where it contributes to cancer cell survival, proliferation, invasion, angiogenesis, and metastasis. Targeting IKKβ has emerged as a promising strategy for cancer therapy, with several inhibitors being developed and some advancing to clinical trials.
WB result of IKKβ Recombinant Rabbit mAb
Primary antibody: IKKβ Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: HeLa whole cell lysate 20 µg
Lane 2: K562 whole cell lysate 20 µg
Lane 3: Jurkat whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 87 kDa
Observed MW: 90 kDa
WB result of IKKβ Recombinant Rabbit mAb
Primary antibody: IKKβ Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: NIH/3T3 whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 87 kDa
Observed MW: 90 kDa
WB result of IKKβ Recombinant Rabbit mAb
Primary antibody: IKKβ Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: PC-12 whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 87 kDa
Observed MW: 90 kDa
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