您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
NGAL Recombinant Rabbit mAb (SDT-473-263)

NGAL Recombinant Rabbit mAb (SDT-473-263)

货号: S0B3349
价格: 1120
规格: 1mg
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    NGAL
  • 分子别名

    Lipocalin-2, Neutrophil gelatinase-associated lipocalin
  • 免疫原

    Recombinant Protein
  • Accession

    P80188
  • 克隆号

    SDT-473-263
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    Sandwich ELISA, CLIA
  • 反应种属 ?

    Hu
  • 交叉反应

    No cross-reactivity against CRP and KIM-1

  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 纯度

    >95% by HPLC
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 稀释度

    [{"application": "ELISA", "dilution": "", "species": ""}, {"application": "Sandwich ELISA", "dilution": "", "species": ""}, {"application": "CLIA", "dilution": "", "species": ""}, {"application": "Lateral Flow", "dilution": "", "species": ""}, {"application": "Dot Blot", "dilution": "", "species": ""}, {"application": "WB", "dilution": "", "species": ""}, {"application": "IP", "dilution": "", "species": ""}, {"application": "IHC-P", "dilution": "", "species": ""}, {"application": "ICC", "dilution": "", "species": ""}, {"application": "IF", "dilution": "", "species": ""}, {"application": "ICFCM", "dilution": "", "species": ""}, {"application": "FCM", "dilution": "", "species": ""}, {"application": "mIHC", "dilution": "", "species": ""}]
背景介绍
  • Neutrophil Gelatinase-Associated Lipocalin (NGAL) is a 25 kDa protein that plays a crucial role in the early diagnosis and monitoring of various diseases, particularly acute kidney injury (AKI) and diabetic nephropathy (DN). NGAL is highly sensitive and specific for detecting AKI, often rising within 2 hours post-injury, well before serum creatinine levels change. This makes it a valuable tool for early intervention, especially in high-risk patients such as those undergoing cardiac surgery or exposed to nephrotoxic agents. In diabetic patients, NGAL serves as an early indicator of renal tubular injury, often preceding the appearance of microalbuminuria. Studies have shown that elevated urinary NGAL levels correlate with the progression of DN, making it a promising biomarker for early detection and management. NGAL is a versatile biomarker with significant clinical utility in early diagnosis, prognosis, and monitoring of kidney-related and other systemic diseases. Its ability to provide early and accurate insights makes it a valuable tool in modern medicine.

  • 配对推荐