PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 1.25μl per million cells in 100μl volum | Ms |
Immunoglobulin D (IgD) is one of the five classes of antibodies, primarily found as a monomer with a molecular weight of approximately 184 kDa and a half-life of 2.8 days. It is predominantly expressed on the surface of mature B cells, where it serves as an antigen receptor alongside IgM, playing a role in B cell activation, proliferation, and differentiation. IgD is also present in mucosal secretions and blood, and it can bind to basophils and mast cells, potentially activating them to release antimicrobial factors and contributing to mucosal immunity. Although its exact function remains enigmatic, IgD is believed to enhance humoral immune responses, participate in B cell memory, and possibly interfere with viral replication. Additionally, IgD may have a role in allergic reactions, though this area requires further investigation.
Flow cytometric analysis of Mouse IgD expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Alexa Fluor® 647 Rat Anti-Mouse CD45R/B220 Antibody and either FITC Rat IgG2a, κ Isotype Control (Left panel) or SDT FITC Rat Anti-Mouse IgD Antibody (Right panel) at 1.25μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
您现在的位置：