您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
Cannabinoid Receptor II Recombinant Rabbit mAb (S-1775-134)

Cannabinoid Receptor II Recombinant Rabbit mAb (S-1775-134)

货号: S0B1330
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    Cannabinoid Receptor II
  • 分子别名

    Cannabinoid receptor 2; CB-2; CB2; hCB2; CX5; CNR2; CB2A; CB2B
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Cell membrane
  • Accession

    P34972
  • 克隆号

    S-1775-134
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    WB
  • 反应种属 ?

    Hu
  • 阳性样本

    HaCaT, Jurkat, THP-1
  • 纯化方式

    Protein A
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度 推荐种属
WB 1:1000 Hu
背景介绍
  • Cannabinoid Receptor II (CB2) protein is a G protein-coupled receptor with seven transmembrane helices, belonging to the rhodopsin-like GPCR superfamily. It is a key component of the endocannabinoid system and is primarily expressed in the peripheral immune system, including immune cells and tissues, with minimal distribution in the central nervous system (CNS). CB2 plays a crucial role in modulating immune responses, particularly in the context of inflammation. Activation of CB2 has been shown to have anti-inflammatory effects, making it a potential therapeutic target for conditions such as neuroinflammation, neuropathic pain, and immune-related disorders. CB2 is also involved in the regulation of cell-mediated and humoral immunity, and its activation can influence the migration and function of immune cells.

  • 免疫印迹

    • WB result of Cannabinoid Receptor II Recombinant Rabbit mAb
      Primary antibody: Cannabinoid Receptor II Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: HaCaT whole cell lysate 20 µg
      Lane 2: Jurkat whole cell lysate 20 µg
      Lane 3: THP-1 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 39 kDa
      Observed MW: 40 kDa