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LAMP1 Recombinant Rabbit mAb (FITC Conjugate) (SDT-405-39)

LAMP1 Recombinant Rabbit mAb (FITC Conjugate) (SDT-405-39)

货号: S0B1779
价格: 1056
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    LAMP1
  • 分子别名

    Lysosome-associated membrane glycoprotein 1; CD107 antigen-like family member A; CD107a
  • 免疫原

    Recombinant Protein
  • 细胞定位

    Cell membrane
  • Accession

    P11279
  • 克隆号

    SDT-405-39
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    ICFCM, ICC
  • 反应种属 ?

    Hu
  • 阳性样本

    HeLa
  • 纯化方式

    Protein A
  • 浓度

    1 mg/ml
  • 标记

    FITC
  • 性状

    Liquid
  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度 推荐种属
ICC 1:50 Hu
ICFCM 1:400 Hu
背景介绍
  • Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The LAMP-1 glycoprotein is a type I transmembrane protein [PMID: 16973206] which is expressed at high or medium levels in at least 76 different normal tissue cell types. It resides primarily across lysosomal membranes [PMID: 2584229], and functions to provide selectins with carbohydrate ligands. LAMP-1 has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells, and may also play a role in tumor cell differentiation and metastasis.

  • 免疫细胞化学

    • ICC shows positive staining in HeLa cells. Anti- LAMP1 (FITC Conjugate) antibody was used at 1/50 dilution (Green) and incubated overnight at 4°C. The cells were fixed with 100% ice-cold methanol and permeabilized with 0.1% PBS-Triton X-100. Nuclei were counterstained with DAPI (Blue).