您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
HIRA Recombinant Rabbit mAb (S-1802-37)

HIRA Recombinant Rabbit mAb (S-1802-37)

货号: S0B1243
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    HIRA
  • 分子别名

    Protein HIRA; TUP1-like enhancer of split protein 1; Tuple1
  • 免疫原

    Recombinant Protein
  • 细胞定位

    Nucleus
  • Accession

    Q61666
  • 克隆号

    S-1802-37
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    WB
  • 反应种属 ?

    Hu, Ms
  • 阳性样本

    HEK-293, HeLa, K562, F9
  • 纯化方式

    Protein A
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度 推荐种属
WB 1:1000 Hu, Ms
背景介绍
  • HIRA, or the Histone chaperone HIRA complex, is a crucial protein complex involved in chromatin remodeling and the regulation of gene expression. It plays a significant role in the deposition of the histone variant H3.3 into nucleosomes, which is essential for DNA replication, repair, and the maintenance of genomic integrity. HIRA is particularly important in embryonic stem cells, where it helps to control the activity of retrotransposons, thereby safeguarding the stability of the genome. Its function in these processes underscores the importance of HIRA in development and the prevention of diseases associated with genomic instability.

  • 免疫印迹

    • WB result of HIRA Recombinant Rabbit mAb
      Primary antibody: HIRA Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: HEK-293 whole cell lysate 20 µg
      Lane 2: HeLa whole cell lysate 20 µg
      Lane 3: K562 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 112 kDa
      Observed MW: 112 kDa

    • WB result of HIRA Recombinant Rabbit mAb
      Primary antibody: HIRA Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: F9 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 112 kDa
      Observed MW: 112 kDa