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Mouse IL-2R alpha/CD25 Protein, hFc tag

Mouse IL-2R alpha/CD25 Protein, hFc tag

货号: S0A1142
价格: 1400
规格: 25μg
介绍: -
其他: -
产品规格

  • 物种

    Mouse

  • 分子别名

    Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, p55, CD25, Il2ra, Il2r

  • Accession

    P01590

  • 表达序列

    Protein sequence (P01590, Glu22-Lys236, with C-hFc tag) ELCLYDPPEVPNATFKALSYKNGTILNCECKRGFRRLKELVYMRCLGNSWSSNCQCTSNSHDKSRKQVTAQLEHQKEQQTTTDMQKPTQSMHQENLTGHCREPPPWKHEDSKRIYHFVEGQSVHYECIPGYKALQRGPAISICKMKCGKTGWTQPQLTCVDEREHHRFLASEESQGSRNSSPESETSCPITTTDFPQPTETTAMTETFVLTMEYK

  • 表达宿主

    HEK293

  • 分子量

    Predicted MW: 26.4 kDa Observed MW: 45-70 kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    with C-hFc tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

  • 稀释度

    [{"application": "ELISA", "dilution": "", "species": ""}, {"application": "Sandwich ELISA", "dilution": "", "species": ""}, {"application": "CLIA", "dilution": "", "species": ""}, {"application": "Lateral Flow", "dilution": "", "species": ""}, {"application": "Dot Blot", "dilution": "", "species": ""}, {"application": "WB", "dilution": "", "species": ""}, {"application": "IP", "dilution": "", "species": ""}, {"application": "IHC", "dilution": "", "species": ""}, {"application": "ICC", "dilution": "", "species": ""}, {"application": "IF", "dilution": "", "species": ""}, {"application": "ICFCM", "dilution": "", "species": ""}, {"application": "FCM", "dilution": "", "species": ""}, {"application": "mIHC", "dilution": "", "species": ""}]
背景介绍

  • The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2 receptor, consisting of alpha (IL2RA), beta (IL2RB) and the common gamma chain (IL2RG). This receptor interacts with interleukin-2, a pleiotropic cytokine which plays an important role in immune homeostasis. Quantification of soluble IL2RA is a useful and simple tool for clinicians to assess immune function in vivo as part of the investigation, management, and prognosis of a broad spectrum of diseases, such as sarcoidosis, Multiple Sclerosis, primary biliary cirrhosis, Chronic immune activation in common variable immunodeficiency (CVID), chronic liver diseases and many more.

  • 生物活性JSON

    • Immobilized IL-2 Protein, Mouse (Cat. No. UA040171) at 2 μg/mL (100 μL/well) can bind Mouse IL-2R alpha/CD25 Protein, His tag with EC50 of 10.5-15.3 ng/ml.

  • 电泳JSON

    • 2μg（R: reducing conditions）