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Lamin A/C Recombinant Rabbit mAb (HRP Conjugate) (S-950-164)

Lamin A/C Recombinant Rabbit mAb (HRP Conjugate) (S-950-164)

货号: S0B1738
价格: 480
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    Lamin A/C
  • 分子别名

    LMNA; LMN1
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Nucleus lamina
  • Accession

    P02545
  • 克隆号

    S-950-164
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    WB
  • 反应种属 ?

    Dg, Gt, Bv, Rb, Hu, Ms, Rt
  • 阳性样本

    HeLa, HUVEC, HepG2, NIH/3T3, C6
  • 预测反应种属
    (反应种属缩写表)

    Pg
  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 标记

    HRP
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20°C as supplied

稀释度
应用 稀释度 推荐种属
WB 1:5000-1:10000 Hu, Ms, Rt
背景介绍
  • Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. Lamin A has a mass of about 74kDa while Lamin C is 65kDa. Mutations in the LMNA gene are associated with several serious human diseases, including Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease type 2B1, and Hutchinson-Gilford progeria syndrome.

  • 免疫印迹

    • WB result of Lamin A/C Recombinant Rabbit mAb (HRP Conjugate)
      Primary antibody: Lamin A/C Recombinant Rabbit mAb (HRP Conjugate) at 1/5000 dilution
      Lane 1: HeLa whole cell lysate 20 µg
      Lane 2: HUVEC whole cell lysate 20 µg
      Lane 3: HepG2 whole cell lysate 20 µg
      Predicted MW: 64, 74 kDa
      Observed MW: 60, 74 kDa

    • WB result of Lamin A/C Recombinant Rabbit mAb (HRP Conjugate)
      Primary antibody: Lamin A/C Recombinant Rabbit mAb (HRP Conjugate) at 1/5000 dilution
      Lane 1: NIH/3T3 whole cell lysate 20 µg
      Predicted MW: 64, 74 kDa
      Observed MW: 60, 74 kDa

    • WB result of Lamin A/C Recombinant Rabbit mAb (HRP Conjugate)
      Primary antibody: Lamin A/C Recombinant Rabbit mAb (HRP Conjugate) at 1/5000 dilution
      Lane 1: C6 whole cell lysate 20 µg
      Predicted MW: 64, 74 kDa
      Observed MW: 60, 74 kDa