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IFN-alpha1 Recombinant Rabbit mAb (SDT-095-163)

IFN-alpha1 Recombinant Rabbit mAb (SDT-095-163)

货号: S0B3324
价格: 5000
规格: 1mg
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    IFNA1
  • 分子别名

    IFN-alpha-1/13, Interferon alpha-D
  • 免疫原

    Recombinant Protein
  • Accession

    P01562
  • 克隆号

    SDT-095-163
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    Sandwich ELISA
  • 反应种属 ?

    Hu
  • 交叉反应

    Doesn’t react with IFN-gamma, IFN-alpha2(≤1ng/ml)

  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 纯度

    >95% by HPLC
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 稀释度

    [{"application": "ELISA", "dilution": "", "species": ""}, {"application": "Sandwich ELISA", "dilution": "", "species": ""}, {"application": "CLIA", "dilution": "", "species": ""}, {"application": "Lateral Flow", "dilution": "", "species": ""}, {"application": "Dot Blot", "dilution": "", "species": ""}, {"application": "WB", "dilution": "", "species": ""}, {"application": "IP", "dilution": "", "species": ""}, {"application": "IHC-P", "dilution": "", "species": ""}, {"application": "ICC", "dilution": "", "species": ""}, {"application": "IF", "dilution": "", "species": ""}, {"application": "ICFCM", "dilution": "", "species": ""}, {"application": "FCM", "dilution": "", "species": ""}, {"application": "mIHC", "dilution": "", "species": ""}]
背景介绍
  • IFN-α is a cytokine that has an immunomodulatory function. It plays an important role not only in antiviral activity but also in several physiologic functions, such as activation of dendritic cells and accelerated expression of major histocompatibility complex I and II molecules that may cause increased antigen presentation. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Among the 13 subtypes of human IFN-alpha, IFN-alpha1 subtype has 2 variants, named IFN-α 1a and IFN-α 1b, that differ from each other in only 1 amino acid, at residue 114. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. IFN-α is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.

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