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PMP22 Recombinant Rabbit mAb (S-754-145)

PMP22 Recombinant Rabbit mAb (S-754-145)

货号: S0B1144
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    PMP22
  • 分子别名

    Peripheral myelin protein 22; PMP-22; Growth arrest-specific protein 3 (GAS-3); GAS3
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Cell membrane
  • Accession

    Q01453
  • 克隆号

    S-754-145
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    WB
  • 反应种属 ?

    Hu, Ms, Rt
  • 阳性样本

    HeLa, SH-SY5Y, mouse brain, PC-12
  • 预测反应种属
    (反应种属缩写表)

    Hr, Bv
  • 纯化方式

    Protein A
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度 推荐种属
WB 1:1000 Hu, Ms, Rt
背景介绍
  • PMP22, or Peripheral Myelin Protein 22, is a protein that is primarily expressed in the compact myelin of the peripheral nervous system. It plays a crucial role in the formation and maintenance of the myelin sheath, which insulates nerve fibers and allows for efficient transmission of nerve impulse. Abnormalities in the PMP22 gene are responsible for a group of inherited peripheral neuropathies, including Charcot-Marie-Tooth disease type 1A (CMT1A), Hereditary Neuropathy with Liability to Pressure Palsies (HNPP) and CMT1E. PMP22-related neuropathies are the most prevalent among the inherited neuropathies, and understanding their clinical presentations and genetic testing is essential for neurologists and geneticists dealing with inherited neuropathy patients.

  • 免疫印迹

    • WB result of PMP22 Recombinant Rabbit mAb
      Primary antibody: PMP22 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: HeLa whole cell lysate 20 µg
      Lane 2: SH-SY5Y whole cell lysate 20 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 18 kDa
      Observed MW: 27 kDa

    • WB result of PMP22 Recombinant Rabbit mAb
      Primary antibody: PMP22 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: mouse brain lysate 20 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 18 kDa
      Observed MW: 27 kDa

    • WB result of PMP22 Recombinant Rabbit mAb
      Primary antibody: PMP22 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: PC-12 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 18 kDa
      Observed MW: 27 kDa