12 months from date of receipt / reconstitution, -20 °C as supplied
应用 | 稀释度 | 推荐种属 |
---|---|---|
WB | 1:1000 | Hu, Ms, Rt |
PMP22, or Peripheral Myelin Protein 22, is a protein that is primarily expressed in the compact myelin of the peripheral nervous system. It plays a crucial role in the formation and maintenance of the myelin sheath, which insulates nerve fibers and allows for efficient transmission of nerve impulse. Abnormalities in the PMP22 gene are responsible for a group of inherited peripheral neuropathies, including Charcot-Marie-Tooth disease type 1A (CMT1A), Hereditary Neuropathy with Liability to Pressure Palsies (HNPP) and CMT1E. PMP22-related neuropathies are the most prevalent among the inherited neuropathies, and understanding their clinical presentations and genetic testing is essential for neurologists and geneticists dealing with inherited neuropathy patients.
WB result of PMP22 Recombinant Rabbit mAb
Primary antibody: PMP22 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: HeLa whole cell lysate 20 µg
Lane 2: SH-SY5Y whole cell lysate 20 µg
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 18 kDa
Observed MW: 27 kDa
WB result of PMP22 Recombinant Rabbit mAb
Primary antibody: PMP22 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: mouse brain lysate 20 µg
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 18 kDa
Observed MW: 27 kDa
WB result of PMP22 Recombinant Rabbit mAb
Primary antibody: PMP22 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: PC-12 whole cell lysate 20 µg
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 18 kDa
Observed MW: 27 kDa