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C1QB Recombinant Rabbit mAb (S-1248-314)

C1QB Recombinant Rabbit mAb (S-1248-314)

货号: S0B1167
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    C1QB
  • 分子别名

    Complement C1q subcomponent subunit B
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Secreted
  • Accession

    P02746
  • 克隆号

    S-1248-314
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    IHC-P, WB
  • 反应种属 ?

    Hu
  • 阳性样本

    human plasma
  • 预测反应种属
    (反应种属缩写表)

    Bv
  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度 推荐种属
WB 1:1000 Hu
IHC-P 1:200-1:500 Hu
背景介绍
  • C1QB, or Complement C1q Subcomponent B, is a component of the serum complement system C1 complex. It combines with C1QA and C1QC chains, as well as with the precursor enzymes C1r and C1s, to form C1, which is the first component of the serum complement system. The function of C1QB involves its globular head interacting with the Fc region of immune complexes, triggering the complement cascade, leading to the attack and clearance of pathogens. C1QB plays a crucial role in host defense, participating in the recognition and clearance of immune complexes, promotion of phagocytosis, regulation of cytokine production, and influencing T lymphocyte maturation. Additionally, C1QB is involved in tissue repair, tumor immune surveillance, and the homeostasis regulation of the central nervous system. The function of C1QB is essential for maintaining immune balance and preventing autoimmune diseases, and its role in various physiological and pathological processes indicates its complex involvement in immune regulation and cellular processes.

  • 免疫印迹

    • WB result of C1QB Recombinant Rabbit mAb
      Primary antibody: C1QB Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: human plasma lysate 5 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 27 kDa
      Observed MW: 27 kDa

  • 免疫组化

    • IHC shows positive staining in paraffin-embedded human lung. Anti-C1BQ antibody was used at 1/400 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human placenta. Anti-C1BQ antibody was used at 1/400 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human breast cancer. Anti-C1BQ antibody was used at 1/400 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

  • 组织表达图谱

    • Expression of C1QB in tumor tissue.

    • Expression of C1QB in human tissue.