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APC-Cy7 Rat Anti-Mouse Ly-6G/Ly-6C(Gr-1) Antibody (S-R425)

APC-Cy7 Rat Anti-Mouse Ly-6G/Ly-6C(Gr-1) Antibody (S-R425)

货号: S0B1702
价格: 1983
规格: 100T
介绍: -
其他: -
产品规格
  • 宿主来源

    Rat
  • 抗原名称

    Ly-6G/Ly-6C(Gr-1)
  • 分子别名

    Lymphocyte antigen 6G; Ly-6G.1
  • 细胞定位

    Cell membrane
  • Accession

    P35461
  • 克隆号

    S-R425
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG2b,k
  • 应用

    FCM
  • 反应种属 ?

    Ms
  • 阳性样本

    C57BL/6 mouse bone marrow
  • 纯化方式

    Protein G
  • 浓度

    20 μg/ml
  • 标记

    APC-Cy7
  • 性状

    Liquid
  • 缓冲体系

    PBS, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度 推荐种属
FCM 5 μl per million cells in 100μl volume Ms
背景介绍
  • Ly-6G protein is a GPI (glycosylphosphatidylinositol)-anchored protein. Ly-6G is primarily expressed on monocytes, neutrophils, and T cells. It plays a crucial role in inhibiting anti-tumor efficacy and T-cell responses. Due to its specific expression on neutrophils, Ly-6G has been widely used as a surface marker in flow cytometry, cell sorting, and immune phenotyping experiments. Unique expression of Ly-6G in bone marrow indicates its involvement in hematopoietic microenvironment, potentially regulating the development or function of immune cells within the bone marrow niche.

  • 流式分析

    • Flow cytometric analysis of Mouse Ly-6G/Ly-6C(Gr-1) expression on C57BL/6 mouse bone marrow. C57BL/6 mouse bone marrow were stained with Brilliant Violet 510™ Rat Anti-Mouse CD11b antibody and either APC-Cy7 Rat IgG2b, κ Isotype Control (Left panel) or SDT APC-Cy7 Rat Anti- Mouse Ly-6G/Ly-6C(Gr-1) antibody (Right panel) at 0.1 μg/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.