PBS pH7.4, containing no preservative
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Ms |
CSF1R, or Colony-Stimulating Factor 1 Receptor, also known as CD115 and M-CSF-R, is a transmembrane receptor that belongs to the type III protein tyrosine kinase receptor family. It is primarily expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts. The natural ligands for CSF1R include CSF1 and IL-34, which directly affect the differentiation and proliferation of tissue macrophages and osteoclasts. CSF1R plays a role in various physiological processes, including regulating the proliferation of early hematopoietic progenitor cells and influencing many physiological processes involved in immunology, metabolism, fertility, and pregnancy. Additionally, CSF1R is involved in modulating the function of tumor-associated macrophages (TAMs), which can suppress tumor immunity. CSF1R also plays an important role in the central nervous system and neurological diseases.
Macrophage depletion efficacy of S0B1139 in C57 mice
WB result of Invivo anti-mouse CSF1R Recombinant mAb
Primary antibody: Invivo anti-mouse CSF1R Recombinant mAb at 1/1000 dilution
Lane 1: M-CSFR His Tag Protein, Mouse 1 µg
Secondary antibody: Goat Anti-rat IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 109 kDa
Observed MW: 80~110 kDa
您现在的位置：