您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
IL-13RA2/CD213a2 Rabbit Polyclonal Antibody

IL-13RA2/CD213a2 Rabbit Polyclonal Antibody

货号: S0B1131
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    IL-13RA2/CD213a2
  • 分子别名

    Interleukin-13 receptor subunit alpha-2; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; Interleukin-13-binding protein
  • 免疫原

    Recombinant Protein
  • 细胞定位

    Cell membrane
  • Accession

    Q14627
  • 抗体类型

    Polyclonal antibody
  • 抗体同种型

    IgG
  • 应用

    WB
  • 反应种属 ?

    Hu, Ms, Rt
  • 阳性样本

    A375, U-87, HeLa, mouse testis, rat testis
  • 纯化方式

    Immunogen Affinity
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度 推荐种属
WB 1:1000 Hu, Ms, Rt
背景介绍
  • IL-13RA2, or Interleukin 13 Receptor Alpha 2, is a protein that has gained significant attention for its role in cancer and as a potential therapeutic target. IL-13RA2 is overexpressed in various cancers, including melanoma, renal cell carcinoma, adrenocortical carcinoma, and several brain tumors. Its expression is associated with tumor invasion, metastasis, and poor prognosis. Unlike the IL-13Rα1, which activates the JAK/STAT pathway, IL-13RA2 was considered a non-signaling receptor due to its short intracellular domain. However, it has been shown to participate in signaling pathways that promote tumor progression, such as those involving AP-1 and ERK.

  • 免疫印迹

    • WB result of IL-13RA2/CD213a2 Rabbit pAb
      Primary antibody: IL-13RA2/CD213a2 Rabbit pAb at 1/1000 dilution
      Lane 1: Daudi whole cell lysate 20 µg
      Lane 2: A375 whole cell lysate 20 µg
      Lane 3: U-87 MG whole cell lysate 20 µg
      Lane 4: HeLa whole cell lysate 20 µg
      Negative control: Daudi whole cell lysate
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 44 kDa
      Observed MW: 70 kDa

    • WB result of IL-13RA2/CD213a2 Rabbit pAb
      Primary antibody: IL-13RA2/CD213a2 Rabbit pAb at 1/1000 dilution
      Lane 1: mouse testis lysate 20 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 44 kDa
      Observed MW: 70 kDa

    • WB result of IL-13RA2/CD213a2 Rabbit pAb
      Primary antibody: IL-13RA2/CD213a2 Rabbit pAb at 1/1000 dilution
      Lane 1: rat testis lysate 20 µg
      Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 44 kDa
      Observed MW: 70 kDa