PBS pH7.4
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 1:2000 | Hu |
CD8A encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
Flow cytometric analysis of human PBMC (human peripheral blood mononuclear cell)labelling Human CD8 antibody at 1/2000 (0.1 μg)dilution (Right) compared with a Mouse lgG1 isotype control (Left).Then cells were stained with CD4 - Alexa Fluor® 647 separately. Gated on total viable cells.
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