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S-RMab®Steroidogenic Factor 1/SF-1 Recombinant Rabbit mAb (SDT-1666-11)

S-RMab®Steroidogenic Factor 1/SF-1 Recombinant Rabbit mAb (SDT-1666-11)

货号: S0B2358
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    Steroidogenic Factor 1/SF-1
  • 分子别名

    STF-1; hSF-1; Adrenal 4-binding protein; Fushi tarazu factor homolog 1; Nuclear receptor subfamily 5 group A member 1; Steroid hormone receptor Ad4BP; NR5A1; AD4BP, FTZF1, SF1
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Nucleus
  • Accession

    Q13285
  • 克隆号

    SDT-1666-11
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    IHC-P
  • 反应种属 ?

    Hu
  • 阳性样本

    human adrenal gland, human testis
  • 纯化方式

    Protein A
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度 推荐种属
IHC-P 1:100 Hu
背景介绍
  • SF-1 (Steroidogenic Factor 1) is a 52-kDa nuclear receptor transcription factor that activates the promoters of many key genes involved in steroidogenesis, adrenal development, and reproduction (CYP11A, CYP11B, CYP21B, AHCH, STAR, etc.) within the body. It is expressed in the adrenal gland and reproductive axis both during fetal development and in adulthood. High expression is observed in the adrenal cortex, pituitary, ovaries (granulosa and theca cells), testes (sertoli and leydig cells), and spleen.

  • 免疫组化

    • IHC shows positive staining in paraffin-embedded human testis. Anti-Steroidogenic Factor 1/SF-1 antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human adrenal gland. Anti-Steroidogenic Factor 1/SF-1 antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human ovarian steroid cell tumor. Anti-Steroidogenic Factor 1/SF-1 antibody was used at 1/100 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

  • 组织表达图谱

    • Expression of Steroidogenic Factor 1/SF-1 in human tissue