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Felis CD21 Protein, His tag

Felis CD21 Protein, His tag

货号: S0A1138
价格: 1000
规格: 25μg
介绍: -
其他: -
产品规格
  • 分子别名

    Complement C3d receptor 2, CR2
  • Accession

    M3WDJ8
  • 表达序列

    Protein sequence (M3WDJ8, Ile21-Pro1038, with C-His tag) ISCDPPPPIKNGWSSYSSGPIPLNTVIRYTCSGNFRLIGERVIFCISKDQVKAIWDKGAPVCEYYNKNSFCSEPIVPGGYRDKTSRPPYRHGDSVTFTCNTNFTMKGNKSVWCRANRTWGPTPLPICESDFPQECTSLPKIPNGHHTGESVGSFAPGLSVTYSCEPGYLLVGEKTIRCLSSGKWSAAFPGCKEAQCEPPGPFLNGEIEGPPSLRVGVTVNFYCNEGYWLQGQPSSRCVIAGQRASWTRMPVCKEILCGPPPSILNGRHTGNPSGNIPYGSMVTYACDPDPEKGVSFILTGKKTIHCTANSQKTGGVWSGPAPRCELSSSAIQCPPPQIPRGHISSGWKEQYSYNDTVVFACTFGFTMKGSKVTRCNGQGAWEPSVPVCEKECQAPPKILNGQKEDGHMVRFDPGTSIKYRCDPGYVLVGEKSIRCTSEGVWTPTAPECKVAECEPIEKQVFKRPRDQFIRPDVNSSCDEGYRLGGSVYQLCQGAIPWFMEHRLCEEITCPPPPVIYNGKHTRSSSENVPYGTTVTYTCNPGPESGVEFILVGESTIRCISNDQERGIWSGPAPVCKLSLPAVQCPPAHVANGYKISGKEAPYFYNDSVTFKCNKGFTLKGSSQIRCKANNTWDPEIPVCEKGCPPPFGLQHGRHTGGNRVLFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEEAPCQPVREDLREPPVHSHVVLVNTSCQEGYQLTGHAYQKCQDAENRVWFQKIPLCKAVHCPPPPVIDHGRPRGVMAEHFLYGNEVSYECDQGFSLLGEKNIRCISDSKGHGSWSGPTPQCFKSPPVTHCPNPEVKHGYKLNKTRSSYAHNDTVYVACNPGFIMNGSNLIRCHTSNQWVPGVPTCIKMAFSGCQPPLDIPNGNHTGGDMARFSPGMSILYSCDQGYLLVGEAFLLCTHEGTWSQPAPYCKEVNCSSPEYINGIQKGLEPGKMYQYGAIVTLECEEGYTLEGSPQSQCQDDHRWNPPLAVCKSPASLAP

  • 表达宿主

    HEK293
  • 分子量

    Predicted MW: 113.1 kDa Observed MW: 160 kDa
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 标记

    Unconjugated
  • 标签

    with C-His tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

  • 稀释度

    [{"application": "ELISA", "dilution": "", "species": ""}, {"application": "Sandwich ELISA", "dilution": "", "species": ""}, {"application": "CLIA", "dilution": "", "species": ""}, {"application": "Lateral Flow", "dilution": "", "species": ""}, {"application": "Dot Blot", "dilution": "", "species": ""}, {"application": "WB", "dilution": "", "species": ""}, {"application": "IP", "dilution": "", "species": ""}, {"application": "IHC", "dilution": "", "species": ""}, {"application": "ICC", "dilution": "", "species": ""}, {"application": "IF", "dilution": "", "species": ""}, {"application": "ICFCM", "dilution": "", "species": ""}, {"application": "FCM", "dilution": "", "species": ""}, {"application": "mIHC", "dilution": "", "species": ""}]
背景介绍
  • Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein-Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells express CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation. Complement receptor 2 interacts with CD19, and, on mature B cells, forms a complex with CD81 (TAPA-1). The CR2-CD19-CD81 complex is often called the B cell co-receptor complex, because CR2 binds to opsonized antigens through attached C3d (or iC3b or C3dg) when the B-cell receptor binds antigen. This results in the B cell having greatly enhanced response to the antigen.

  • 电泳JSON

    • 2μg(R: reducing conditions)