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FITC Rat anti-Mouse CD4 antibody (S-R542)

FITC Rat anti-Mouse CD4 antibody (S-R542)

货号: S0B1646
价格: 300
规格: 50T
介绍: -
其他: -
产品规格
  • 宿主来源

    Rat
  • 抗原名称

    CD4
  • 分子别名

    T-cell surface glycoprotein CD4; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3
  • 细胞定位

    Cell membrane
  • Accession

    P06332
  • 克隆号

    S-R542
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG2b,k
  • 应用

    FCM
  • 反应种属 ?

    Ms
  • 阳性样本

    C57BL/6 mouse splenocytes
  • 纯化方式

    Protein G
  • 浓度

    20 μg/ml
  • 标记

    FITC
  • 性状

    Liquid
  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
稀释度
应用 稀释度 推荐种属
FCM 5 μl per million cells in 100μl volume Ms
背景介绍
  • CD4 is a glycoprotein molecule found on the surface of certain white blood cells, primarily T lymphocytes, and is known as the T helper cell marker. CD4+ T cells play a crucial role in the immune system as they act as the "conductors" of the immune response, helping to coordinate the body's defense against pathogens such as bacteria, viruses, and other foreign invaders. CD4+ T cells are a type of T lymphocyte. When a pathogen enters the body, the immune response process begins with macrophages engulfing the pathogen and releasing antigen information, which is then passed on to CD4+ T cells. This antigen transfer leads to the production of antibodies that can easily attach to the pathogen, making it easier for macrophages to capture and engulf it. Therefore, CD4+ T cells are essential as they act as helpers and "eyes" of the immune system, transmitting pathogen information. CD4+ T cells are also a key indicator of the immune system's damage in HIV-infected patients, as HIV targets these cells. The count of CD4+ T cells can directly reflect the immune function and is the most explicit indicator of the immune system's damage in HIV patients.