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Invivo anti-mouse/rat IL-1β Recombinant mAb

Invivo anti-mouse/rat IL-1β Recombinant mAb

货号: S0B1071
价格: 700
规格: 1mg
介绍: -
其他: -
产品规格
  • 宿主来源

    Armenian hamster
  • 抗原名称

    IL-1β
  • 分子别名

    Interleukin-1 beta; IL-1 beta
  • 细胞定位

    Secreted
  • Accession

    P10749, Q63264
  • 克隆号

    S-R479
  • 抗体类型

    Armenian hamster mAb
  • 抗体同种型

    IgG
  • 应用

    in vivo IL-1β neutralization, in vitro IL-1β neutralization, WB
  • 反应种属 ?

    Ms, Rt
  • 纯化方式

    Protein G
  • 浓度

    5 mg/ml
  • 内毒素含量

    <2EU/mg
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, containing no preservative

  • 储存条件

    2 to 8 °C for 2 weeks under sterile conditions;

    -20 °C for 3 months under sterile conditions; 

    -80 °C for 24 months under sterile conditions.

    Please avoid repeated freeze-thaw cycles.

稀释度
应用 稀释度 推荐种属
WB 1:1000 Ms, Rt
背景介绍
  • IL-1β (Interleukin-1 beta) is a crucial pro-inflammatory cytokine primarily produced by activated monocytes and macrophages, but it can also be expressed in various cell types, including epithelial cells, endothelial cells, fibroblasts, synovial cells, neurons, mast cells, and glial cells. The biological functions of IL-1β are extensive, and it is involved in various autoimmune inflammatory responses and cellular activities, including cell proliferation, differentiation, and apoptosis. It also participates in the regulation of IL-6 and TNF-α and activates vascular adhesion molecules such as ICAM1. IL-1β plays a key role in the acute-phase response, including fever, acute protein synthesis, anorexia, and somnolence.

  • 免疫印迹

    • WB result of Invivo anti-mouse/rat IL-1β Recombinant Rabbit mAb
      Primary antibody: Invivo anti-mouse/rat IL-1β Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: IL-1β Protein, Mouse 10 ng
      Lane 2: IL-1β Protein, Rat 10 ng
      Secondary antibody: Goat Anti-Armenian Hamste IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 31 kDa
      Observed MW: 16 kDa