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Alexa Fluor® 488 Mouse Anti-Human CD38 Antibody (S-R507-1)

Alexa Fluor® 488 Mouse Anti-Human CD38 Antibody (S-R507-1)

货号: S0B1635
价格: 650
规格: 20T
介绍: -
其他: -
产品规格

  • 宿主来源

    Mouse

  • 抗原名称

    CD38

  • 分子别名

    2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1 (ADPRC 1); Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1); T10

  • 细胞定位

    Membrane

  • Accession

    P28907

  • 克隆号

    S-R507-1

  • 抗体类型

    Mouse mAb

  • 抗体同种型

    IgG1

  • 应用

    FCM

  • 反应种属 ?

    Hu

  • 阳性样本

    human PBMC

  • 纯化方式

    Protein G

  • 浓度

    0.2mg/ml

  • 标记

    Alexa Fluor® 488

  • 性状

    Liquid

  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
稀释度
应用 稀释度 推荐种属
FCM 5 μl per million cells in 100μl volume Hu
背景介绍

  • CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.

  • 流式分析

    • Multiparameter flow cytometric analysis of Human CD38 expression on human PBMC (human peripheral blood mononuclear cell). Human PBMC were stained with Brilliant Violet 421™ Mouse Anti-Human CD3 antibody and either Alexa Fluor® 488 Mouse IgG1, κ Isotype Control (Left panel) or SDT Alexa Fluor® 488 Mouse Anti-Human CD38 Antibody (Right panel) at 1 μg/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.