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PE Mouse Anti-Human CD8α Antibody (S-1036-34)

PE Mouse Anti-Human CD8α Antibody (S-1036-34)

货号: S0B1634
价格: 845
规格: 20T
介绍: -
其他: -
产品规格
  • 宿主来源

    Mouse
  • 抗原名称

    CD8α
  • 分子别名

    T-lymphocyte differentiation antigen T8/Leu-2; T-cell surface glycoprotein CD8 alpha chain; MAL; CD8a
  • 免疫原

    Recombinant Protein
  • 细胞定位

    Cell membrane
  • Accession

    P01732
  • 克隆号

    S-1036-34
  • 抗体类型

    Mouse mAb
  • 抗体同种型

    IgG1,k
  • 应用

    FCM
  • 反应种属 ?

    Hu
  • 阳性样本

    human PBMC
  • 纯化方式

    Protein G
  • 浓度

    20μg/ml
  • 标记

    PE
  • 性状

    Liquid
  • 缓冲体系

    PBS, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度 推荐种属
FCM 5 μl per million cells in 100μl volume Hu
背景介绍
  • CD8A encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

  • 流式分析

    • Multiparameter flow cytometric analysis of Human CD8 expression on human PBMC (human peripheral blood mononuclear cell). Human PBMC were stained with Brilliant Violet 421™ Mouse Anti-Human CD4 antibody and either Phycoerythrin Mouse IgG1, κ Isotype Control (Left panel) or SDT PE Mouse Anti-Human CD8 Antibody (Right panel) at 0.1 μg/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.