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Mouse Anti-Human CD40 Antibody (S-R530)

Mouse Anti-Human CD40 Antibody (S-R530)

货号: S0B1008
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Mouse
  • 抗原名称

    CD40
  • 分子别名

    B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40
  • 细胞定位

    Secreted, Cell membrane
  • Accession

    P25942
  • 克隆号

    S-R530
  • 抗体类型

    Mouse mAb
  • 抗体同种型

    IgG2b
  • 应用

    FCM
  • 反应种属 ?

    Hu
  • 阳性样本

    human PBMC
  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4
  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度 推荐种属
FCM 1:2000 Hu
背景介绍
  • The CD40 is a type I transgender protein that is transmitted in the immune system's B cells and special antigen to the surface of the cells and many non -hematopoietic cell types and cancer cells. It belongs to the TNF receptor super family.CD40 is expressed in B cells, foam dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. CD40 interacts with CD40 Ligand (CD40L/TNFSF5).CD40/CD40L is essential for the beginning and progress of cells and body fluid adaptive immunity, and it is an important area of concern in the study of tumor immunology, neurodegeneration, vascular disease and inflammatory diseases.

  • 流式分析

    • Flow cytometric analysis of human PBMC (human peripheral blood mononuclear cell) labelling Human CD40 antibody at 1/2000 (0.1 μg) dilution (Right) compared with a Mouse monoclonal IgG isotype control (Left). Goat Anti - Mouse IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD19 - Brilliant Violet 421™ separately. Events were gated on viable lymphocytes.