您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
BRCA2 Recombinant Rabbit mAb (S-1485-4)

BRCA2 Recombinant Rabbit mAb (S-1485-4)

货号: S0B0989
价格: 400
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    BRCA2
  • 分子别名

    Breast cancer type 2 susceptibility protein, Fanconi anemia group D1 protein, FACD, FANCD1
  • 免疫原

    Recombinant Protein
  • 细胞定位

    Cytoplasm, Nucleus
  • Accession

    P51587
  • 克隆号

    S-1485-4
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    WB
  • 反应种属 ?

    Hu
  • 阳性样本

    HeLa, MDA-MB-231
  • 纯化方式

    Protein A
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度 推荐种属
WB 1:1000 Hu
背景介绍
  • The BRCA2 protein is a crucial component in maintaining genomic stability and is involved in various cellular functions such as homologous recombination, G2 checkpoint control, and protection of stalled replication forks. BRCA2 is also known to interact with numerous other proteins and has roles in DNA replication, including stabilizing stalled replication forks and protecting them from degradation. Mutations in the BRCA2 gene can lead to a deficiency in these repair mechanisms, which is why individuals with BRCA2 mutations are at an increased risk for developing certain types of cancer, particularly breast and ovarian cancer.

  • 免疫印迹

    • WB result of BRCA2 Recombinant Rabbit mAb
      Primary antibody: BRCA2 Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: HeLa whole cell lysate 20 µg
      Lane 2: MDA-MB-231 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 384 kDa
      Observed MW: 280 kDa