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Thyroglobulin Recombinant Rabbit mAb (SDT-209-231)

Thyroglobulin Recombinant Rabbit mAb (SDT-209-231)

货号: S0B3310
价格: 1710
规格: 1mg
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    Thyroglobulin 
  • 分子别名

    Thyroglobulin, TG
  • 免疫原

    Native protein
  • Accession

    P01266
  • 克隆号

    SDT-209-231
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    Sandwich ELISA, CLIA
  • 反应种属 ?

    Hu
  • 交叉反应

    Does not recognize Hemoglobin, TSH
  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 纯度

    >95% by HPLC
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300
  • 储存条件

    12 months from date of receipt, 2 to 8 °C as supplied

  • 稀释度

背景介绍
  • Thyroglobulin (Tg) is a large, iodinated glycoprotein that serves as the precursor for the thyroid hormones thyroxine (T4) and triiodothyronine (T3). It is exclusively synthesized in the thyroid follicular cells and stored in the colloid of the thyroid follicles. Thyroglobulin contains numerous tyrosine residues that are iodinated and coupled to form T4 and T3. The hormones are then released into the bloodstream through a process involving endocytosis of thyroglobulin and its proteolysis within the lysosomes of thyroid cells. Tg is a significant biomarker for thyroid status and is used clinically to monitor patients with thyroid cancer. A subsequent elevation of the thyroglobulin level is an indication of recurrence of papillary or follicular thyroid carcinoma. In other words, a rise in thyroglobulin levels in the blood may be a sign that thyroid cancer cells are growing and/or the cancer is spreading. Hence, thyroglobulin levels in the blood are mainly used as a tumor marker for certain kinds of thyroid cancer (particularly papillary or follicular thyroid cancer). Thyroglobulin is not produced by medullary or anaplastic thyroid carcinoma. Thyroglobulin levels are tested via a simple blood test. Tests are often ordered after thyroid cancer treatment.

  • 配对推荐

    • Does not recognize TSH, Hemoglobin.