Pro143-Ser288
17 kDa (Reducing)
20mM Tris, 500mM NaCl, pH8.0
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
1. J Biol Chem. 1996 Jun 21;271(25):15292-7.
2. Biosci Rep. 2017 Apr 10;37(2): BSR20170173.Print 2017 Apr 28.
3. Biochem Biophys Res Commun. 1986 Mar 13;135(2):541-8.
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.
Measured in a cell proliferation assay using Balb/3T3 mouse fibroblast cells, the EC50 for this effect is less than 0.1ng/ml.
Measured in a cell proliferation assay using Balb/3T3 mouse fibroblast cells, the EC50 for this effect is less than 0.1ng/ml.
1μg (R: reducing condition, N: non-reducing condition).
>95% as determined by RP-HPLC.
Immobilized FGF-basic(146aa) Protein, Human (Cat. No. UA040145) at 2.0μg/mL (100μL/well) can bind Glypican 1/GPC1 His Tag Protein, human (Cat. No. UA011160) with EC50 of 18.49-26.03ng/mL.
Immobilized FGF-basic(146aa) Protein, Human (Cat. No.UA040145) at 2.0μg/mL (100μL/well) can bind GPC3 Fc Chimera Protein, Human (Cat. No. UA010680) with EC50 of 4.99-7.73 ng/mL.
Immobilized FGF-basic(146aa) Protein, Human (Cat. No. UA040145) at 2.0μg/mL (100μL/well) can bind GPC3 His Tag Protein, Human (Cat. No. UA010073) with EC50 of 21.65-30.89 ng/mL.
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