95-100kDa (Reducing)
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
1. Chen R ,Cao J ,Chen J , et al.Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma[J].World Journal of Gastroenterology,2012,18(48):7251-7261. 2. 2. Long Z ,Zhou M ,Fu J , et al.Association between cadherin-17 expression and pathological characteristics of gastric cancer:A meta-analysis[J].World Journal of Gastroenterology,2015,21(12):3694-3705.
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins.Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region,7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. Cadherins preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. It's also involved in intestinal peptide transport.
1μg (R: reducing condition, N: non-reducing condition).
Immobilized Biotinylated CDH17/LI-cadherin His&Avi Tag, Human (Cat. No. UA010744) at 2 μg/mL on Streptavidin precoated (0.5μg/well) plate, can bind Cadherin 17 Recombinant Rabbit mAb (SDT-736-23) (Cat. No. S0B2291) with EC50 of 19.73-27.06ng/ml.
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