您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
Biotinylated Fc γ RIIB/CD32b His&Avi Tag Protein, Cynomolgus

Biotinylated Fc γ RIIB/CD32b His&Avi Tag Protein, Cynomolgus

货号: UA010742
价格: 2800
规格: 25μg
介绍: -
其他: -
产品规格
  • 物种

    Cynomolgus
  • 分子别名

    FCGR2B/C, CD32b/c, Fc RII-b/c, Fc-gamma RII-b/c, CD32, FCG2, IGFR2, CDw32
  • Accession

    Q8SPW3
  • 表达序列

    Ala 46-Pro 224, with C-10*His and Avi tag
  • 表达宿主

    HEK293
  • 分子量

    30-35kDa (Reducing)
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 标记

    Biotin
  • 标签

    Avi Tag, His Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, pH7.4.
  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
  • 储存条件

    ·12 months from date of receipt, -20 to -70 °C as supplied. ·1 month, 2 to 8 °C under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Christopher T. Rankin, Maria-Concetta Veri, Sergey Gorlatov, Nadine Tuaillon, Steve Burke, Ling Huang, H. David Inzunza, Hua Li, Shannon Thomas, Syd Johnson, Jeffrey Stavenhagen, Scott Koenig, Ezio Bonvini: CD32B, the human inhibitory Fc-γ receptor IIB, as a target for monoclonal antibody therapy of B-cell lymphoma, Blood (2006) 108 (7): 2384–2391.

  • 稀释度

背景介绍
  • IgG Fc region receptors are members of the Ig superfamily that play roles in activating or inhibiting immune responses such as degranulation, phagocytosis, ADCC, cytokine release, and B-cell proliferation. There are three genes for human Fc γ RII /CD32 (A, B, and C) and one for mouse Fc γ RII B (CD32B). CD32 is a low affinity receptor for IgG. CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis.

  • 电泳JSON

    • 1μg (R: reducing condition, N: non-reducing condition).