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NAP-2/CXCL7 Protein, Human

货号: UA040189

价格: 810

规格: 10μg

介绍: -

其他: -

产品规格

物种

Human
分子别名

PPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL-7, LA-PF4, LDGF, MDGF, NAP2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, pro-platelet basic protein
Accession

P02775
表达序列

Ala59-Asp128
表达宿主

E.coli
分子量

9kDa (Reducing)
纯度

＞95% by SDS-PAGE
内毒素含量

<0.1EU/μg
标记

Unconjugated
标签

No Tag
性状

Lyophilized Powder
缓冲体系

20mM Tris, 300mM NaCl, pH8.0
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

Wang YH, Shen CY, Lin SC, Kuo WH, Kuo YT, Hsu YL, Wang WC, Lin KT, Wang LH. Monocytes secrete CXCL7 to promote breast cancer progression. Cell Death Dis. 2021 Nov 17;12(12):1090. doi: 10.1038/s41419-021-04231-4. PMID: 34789744; PMCID: PMC8599470.

背景介绍

Neutrophil Activating Peptide 2 (NAP-2), also known as CXCL7, is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Recently, it has been shown that CXCL7 is secreted by tumor infiltrating monocytes, to stimulate cancer cell migration, invasion, and metastasis, contributing to the promotion of breast cancer progression. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.