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FGF-basic Protein, Bovine

FGF-basic Protein, Bovine

货号: UA040197
价格: 400
规格: 10μg
介绍: -
其他: -
产品规格

  • 物种

    Bovine

  • 分子别名

    bFGF,FGF-2;Heparin-binding growth factor 2;Basic fibroblast growth factor，FGFB,HBGF-2;FGF2; Fibroblast Growth Factor 2 (Basic)

  • Accession

    P03969

  • 表达序列

    Pro10-Ser155

  • 表达宿主

    E.coli

  • 分子量

    17kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 活性

    <1ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM Tris, 500mM NaCl, pH8.0.

  • 溶解方法

    Reconstitute at 0.5-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. J Biol Chem. 1996 Jun 21;271(25):15292-7.
    2. Biosci Rep. 2017 Apr 10;37(2): BSR20170173.
    3. Biochem Biophys Res Commun. 1986 Mar 13;135(2):541-8.

  • 稀释度

背景介绍

  • Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.

  • 生物活性JSON

    • Measured in a cell proliferation assay using Balb/3T3 mouse fibroblast cells, the EC50 for this effect is less than1ng/ml.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).