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FITC Rat Anti-Mouse CD8β Antibody (S-R484)

FITC Rat Anti-Mouse CD8β Antibody (S-R484)

货号: S0B5545
价格: 300
规格: 25T
介绍: -
其他: -
产品规格
  • 宿主来源

    Rat
  • 抗原名称

    CD8β
  • 分子别名

    T-cell surface glycoprotein CD8 beta chain; Lymphocyte antigen 3; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein Lyt-3; Cd8b1; Ly-3; Lyt-3; Lyt3; Cd8b
  • 细胞定位

    Membrane
  • Accession

    P10300
  • 克隆号

    S-R484
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG1,k
  • 应用

    FCM
  • 反应种属 ?

    Ms
  • 纯化方式

    Protein G
  • 浓度

    0.2 mg/ml
  • 标记

    FITC
  • 性状

    Liquid
  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度 推荐种属
FCM 5μl per million cells in 100μl volume Ms
背景介绍
  • CD8β is a protein that, along with CD8α, forms the CD8 co-receptor complex on the surface of cytotoxic T cells. This complex plays a crucial role in the immune response by facilitating the interaction between cytotoxic T cells and antigen - presenting cells. CD8β helps stabilize the binding of the T cell receptor to MHC class I molecules on the antigen - presenting cell, thereby enhancing the specificity and efficiency of the T cell - mediated immune response. This interaction is essential for the activation of cytotoxic T cells, which can then target and destroy infected or malignant cells.

  • 流式分析

    • Flow cytometric analysis of Mouse CD8β expression on BALB/c mouse splenocytes. BALB/c mouse splenocytes were stained with Alexa Fluor® 647 Rat Anti-Mouse CD8a antibody and either FITC Mouse IgG1, κ Isotype Control (Left panel) or SDT FITC Rat Anti-Mouse CD8β Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.