Protein sequence (Q9Y3D6, Met1-Gly122, with C-His tag) MEAVLNELVSVEDLLKFEKKFQSEKAAGSVSKSTQFEYAWCLVRSKYNDDIRKGIVLLEELLPKGSKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQTEPQNNQAKELERLIDKAMKKDG
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.
12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
Mitochondrial fission 1 protein (Fis1) is a key regulator in mitochondrial fission, a process critical for maintaining mitochondrial dynamics and cellular homeostasis. Localized to the outer mitochondrial membrane, Fis1 recruits cytosolic dynamin-related proteins (e.g., Drp1) to drive mitochondrial fragmentation. Dysregulation of Fis1-mediated fission is linked to various cellular stress responses, apoptosis, and diseases such as neurodegenerative disorders and cancer. Research focuses on its interaction networks, post-translational modifications, and roles in mitochondrial quality control, shedding light on mechanisms underlying mitochondrial dysfunction and potential therapeutic targets.
2μg（R: reducing conditions）
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