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Alexa Fluor® 647 Rat Anti-Human CD294 Antibody (S-2867)

Alexa Fluor® 647 Rat Anti-Human CD294 Antibody (S-2867)

货号: S0B5538
价格: 800
规格: 25T
介绍: -
其他: -
产品规格
  • 宿主来源

    Rat
  • 抗原名称

    CD294
  • 分子别名

    Prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CRTH2; DL1R; GPR44; PTGDR2
  • 细胞定位

    Cell membrane
  • Accession

    Q9Y5Y4
  • 克隆号

    S-2867
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG2a,k
  • 应用

    FCM
  • 反应种属 ?

    Hu
  • 阳性样本

    human PBMC
  • 纯化方式

    Protein G
  • 浓度

    0.2 mg/ml
  • 标记

    Alexa Fluor® 647
  • 性状

    Liquid
  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度 推荐种属
FCM 1.25μl per million cells in 100μl volume Hu
背景介绍
  • CD294, also known as CRTH2, PTGDR2, or GPR44, is a seven-transmembrane G protein-coupled receptor primarily expressed on Th2 cells, eosinophils, basophils, and type-2 innate lymphoid cells (ILC2). It is involved in mediating the chemotaxis of these cells to sites of allergic inflammation, such as the asthmatic lung, and plays a role in preventing apoptosis in Th2 cells.

  • 流式分析

    • Flow cytometric analysis of Human CD294 expression on human PBMC (human peripheral blood mononuclear cell). Human PBMC were stained with FITC Mouse Anti-Human CD123 antibody and either Alexa Fluor® 647 Rat IgG2a, κ Isotype Control (Left panel) or SDT Alexa Fluor® 647 Rat Anti-Human CD294 Antibody (Right panel) at 1.25 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.