PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Hu |
TLR7, or Toll-like receptor 7, is a protein that plays a crucial role in the innate immune system. It is a member of the Toll-like receptor family, which are pattern recognition receptors that detect pathogen-associated molecular patterns (PAMPs). TLR7 is primarily expressed in immune cells such as plasmacytoid dendritic cells and macrophages, and it specifically recognizes single-stranded RNA from viruses, helping to initiate an immune response against viral infections. Activation of TLR7 leads to the production of type I interferons and pro-inflammatory cytokines, which are vital for antiviral defense. Additionally, TLR7 has been implicated in autoimmune diseases due to its potential to recognize self-RNAs under certain conditions, and it is also a target for research in the development of antiviral therapies and immune modulators.
WB result of TLR7 Recombinant Rabbit mAb
Primary antibody: TLR7 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: 293T whole cell lysate 20 µg
Lane 2: Ramos whole cell lysate 20 µg
Lane 3: Daudi whole cell lysate 20 µg
Negative control: 293T whole cell lysate
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 121 kDa
Observed MW: 74, 130 kDa
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