PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Hu |
Klf4, also known as Krüppel-like factor 4, is a transcription factor that plays a crucial role in various biological processes. It is involved in cell differentiation, proliferation, and apoptosis, and is highly expressed in epithelial tissues such as the gastrointestinal tract and skin. Klf4 regulates the expression of numerous genes by binding to specific DNA sequences in their promoters, thereby modulating cellular functions. In the context of stem cell biology, Klf4 is one of the four Yamanaka factors used to reprogram somatic cells into induced pluripotent stem cells (iPSCs), highlighting its significance in cellular reprogramming and regenerative medicine. Additionally, Klf4 has been implicated in maintaining the integrity of the intestinal barrier and has potential implications in cancer development and progression, making it an important target for therapeutic interventions.
WB result of Klf4 Recombinant Rabbit mAb
Primary antibody: Klf4 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: HT-29 whole cell lysate 20 µg
Lane 2: HCT 116 whole cell lysate 20 µg
Lane 3: MCF7 whole cell lysate 20 µg
Lane 4: Ramos whole cell lysate 20 µg
Lane 5: HepG2 whole cell lysate 20 µg
Lane 6: PC-3 whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 54 kDa
Observed MW: 54 kDa
This blot was developed with high sensitivity substrate
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