PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Primary antibody:12 months from date of receipt / reconstitution, -20 °C as supplied
IHC detection kit:12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用 | 稀释度 | 推荐种属 |
---|---|---|
IHC | 1:500 |
货号 | 产品名称 | 反应种属 | 应用 | 规格 | 数量 |
---|---|---|---|---|---|
S0B2245 | CD11c Recombinant Rabbit mAb (SDT-396-48) | Hu | IHC-P,WB,IP | 25μl | 1 |
S0C2011 | Anti-Rabbit and Mouse HRP-DAB IHC detection kit (2-step) | Rb,Ms | IHC-P | 5ml(for50slides) | 1 |
CD11c, also known as Integrin, is an integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. CD11c is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias. The reagent can complete 50 slides for IHC experiment and the primary antibody is excessive.