PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Primary antibody:12 months from date of receipt / reconstitution, -20 °C as supplied
IHC detection kit:12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
| 应用 | 稀释度 |
|---|---|
| IHC | 1:1000 |
| 货号 | 产品名称 | 反应种属 | 应用 | 规格 | 数量 |
|---|---|---|---|---|---|
| S0B2159 | CD138 Recombinant Rabbit mAb (SDT-R120) | Hu | IHC-P,ICC | 25μl | 1 |
| S0C2011 | Anti-Rabbit and Mouse HRP-DAB IHC detection kit (2-step) | Rb,Ms | IHC-P | 5ml(for50slides) | 1 |
Syndecan-1 (CD138) is mostly restricted to epithelia, and bears heparan sulfate chains that are capable of interacting with a large array of polypeptides, including extracellular matrix components and potent mediators of proliferation, adhesion and migration. For this reason, it has been studied extensively with respect to carcinomas and tumor progression. Frequently, but not always, syndecan-1 levels decrease as tumor grade, stage and invasiveness and dedifferentiation increase. However, in some tumors, levels of syndecan-1 increase, but the characterization of its distribution is relevant. There can be loss of membrane staining, but acquisition of cytoplasmic and/or nuclear staining that is abnormal. Moreover, the appearance of syndecan-1 in the tumor stroma, either associated with its cellular component or the collagenous matrix, is nearly always a sign of poor prognosis [PMID: 33921767]. The reagent can complete 50 slides for IHC experiment and the primary antibody is excessive.
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