PBS pH7.4
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 1:200 | Ms |
CD107b, also known as lysosome-associated membrane protein 2 (LAMP-2), is a highly glycosylated type I transmembrane protein with a molecular weight of approximately 105–120 kDa. It is primarily located in the lysosomal/endosomal membranes of nearly all cells and can be transiently expressed on the surface of activated platelets, activated lymphocytes, and some tumor cell lines. LAMP-2 plays crucial roles in various cellular processes, including cell adhesion, cellular homeostasis, autophagocytosis, antigen presentation, and protection of the lysosome. Additionally, it may be involved in tumor cell metastasis by mediating adhesion to vascular endothelium.
Flow cytometric analysis of BALB/c mouse peritoneal exudates cells labelling Mouse CD107b (Mac-3) antibody at 1/200 dilution (1 μg) / (Right panel) compared with a Rat IgG1, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD11b - Brilliant Violet 421™ Antibody separately.
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