您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
Human Intrinsic Factor/CBLIF Protein, His tag

Human Intrinsic Factor/CBLIF Protein, His tag

货号: S0A0173
价格: 900
规格: 10μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • 分子别名

    Cobalamin binding intrinsic factor, Gastric intrinsic factor, Intrinsic factor (IF; INF), GIF, IFMH
  • Accession

    P27352
  • 表达序列

    Protein sequence (P27352, Ser19-Try417, with C-His tag) STQTQSSCSVPSAQEPLVNGIQVLMENSVTSSAYPNPSILIAMNLAGAYNLKAQKLLTYQLMSSDNNDLTIGQLGLTIMALTSSCRDPGDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILNEIKQGKFHNPMSIAQILPSLKGKTYLDVPQVTCSPDHEVQPTLPSNPGPGPTSASNITVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSGVTPLNEGVADYIPFNHEHITANFTQY

  • 表达宿主

    HEK293
  • 分子量

    Predicted MW: 45.1 kDa Observed MW: 54 kDa
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <1EU/μg
  • 标记

    Unconjugated
  • 标签

    with C-His tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied.
    6 months, -20 to -70 °C under sterile conditions after reconstitution.
    1 week, 2 to 8 °C under sterile conditions after reconstitution.
    Please avoid repeated freeze-thaw cycles.

  • 稀释度

    [{"application": "ELISA", "dilution": "", "species": ""}, {"application": "Sandwich ELISA", "dilution": "", "species": ""}, {"application": "CLIA", "dilution": "", "species": ""}, {"application": "Lateral Flow", "dilution": "", "species": ""}, {"application": "Dot Blot", "dilution": "", "species": ""}, {"application": "WB", "dilution": "", "species": ""}, {"application": "IP", "dilution": "", "species": ""}, {"application": "IHC", "dilution": "", "species": ""}, {"application": "ICC", "dilution": "", "species": ""}, {"application": "IF", "dilution": "", "species": ""}, {"application": "mIHC", "dilution": "", "species": ""}, {"application": "ChIP", "dilution": "", "species": ""}]
背景介绍
  • Cobalamin binding intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. Its main function is to bind to vitamin B₁₂ (cobalamin) in the digestive tract. This binding protects cobalamin from degradation and facilitates its absorption in the ileum of the small intestine. The complex of intrinsic factor and cobalamin is recognized by specific receptors on the ileal epithelial cells, allowing for the efficient uptake of vitamin B₁₂ into the bloodstream. Deficiency of intrinsic factor can lead to pernicious anemia, as it impairs the body's ability to absorb vitamin B₁₂, which is essential for normal hematopoiesis and neurological function.

  • 电泳JSON

    • 2μg(R: reducing conditions)