PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
应用 | 稀释度 | 推荐种属 |
---|---|---|
FCM | 5μl per million cells in 100μl volume | Ms |
CD36 is a heavily glycosylated 80kD integral membrane protein widely expressed on platelets, immune cells, adipocytes, myocytes, enterocytes, enteroendocrine cells, and other cell types. It is a member of the class B scavenger receptor family and functions as a pattern recognition receptor. CD36 has a diverse range of ligands and physiological functions, including the uptake of modified lipids and apoptotic cells, long-chain fatty acid transport, adhesion, and angiogenesis. It plays a role in various pathological conditions such as atherosclerosis, diabetes, and cardiomyopathy. In the gut, CD36 promotes absorption of long-chain fatty acids and participates in carotenoid uptake for vitamin A metabolism. It also acts as a receptor for thrombospondin-1 and several other proteins containing thrombospondin type I repeats, functioning as an endogenous negative regulator of angiogenesis on microvascular endothelial cells.
Flow cytometric analysis of Mouse CD36 expression on mouse peritoneal exudates cells. Mouse peritoneal exudates cells were stained with SDT FITC Rat Anti-Mouse F4/80 Antibody (S0B5113) at 5 μl/test and either Alexa Fluor® 647 Armenian Hamster IgG Isotype Control (Left panel) or SDT Alexa Fluor® 647 Armenian Hamster Anti-Mouse CD36 Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.