您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
Alexa Fluor® 647 Armenian hamster Anti-Mouse CD36 Antibody (S-R615)

Alexa Fluor® 647 Armenian hamster Anti-Mouse CD36 Antibody (S-R615)

货号: S0B5443
价格: 400
规格: 20T
介绍: -
其他: -
产品规格
  • 宿主来源

    Armenian hamster
  • 抗原名称

    CD36
  • 分子别名

    Platelet glycoprotein 4; Glycoprotein IIIb (GPIIIB); PAS IV; PAS-4; Platelet glycoprotein IV (GPIV)
  • 细胞定位

    Cell membrane
  • Accession

    Q08857
  • 克隆号

    S-R615
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    FCM
  • 反应种属 ?

    Ms
  • 阳性样本

    mouse peritoneal exudates cells
  • 纯化方式

    Protein G
  • 浓度

    50 μg/ml
  • 标记

    Alexa Fluor® 647
  • 性状

    Liquid
  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
稀释度
应用 稀释度 推荐种属
FCM 5μl per million cells in 100μl volume Ms
背景介绍
  • CD36 is a heavily glycosylated 80kD integral membrane protein widely expressed on platelets, immune cells, adipocytes, myocytes, enterocytes, enteroendocrine cells, and other cell types. It is a member of the class B scavenger receptor family and functions as a pattern recognition receptor. CD36 has a diverse range of ligands and physiological functions, including the uptake of modified lipids and apoptotic cells, long-chain fatty acid transport, adhesion, and angiogenesis. It plays a role in various pathological conditions such as atherosclerosis, diabetes, and cardiomyopathy. In the gut, CD36 promotes absorption of long-chain fatty acids and participates in carotenoid uptake for vitamin A metabolism. It also acts as a receptor for thrombospondin-1 and several other proteins containing thrombospondin type I repeats, functioning as an endogenous negative regulator of angiogenesis on microvascular endothelial cells.

  • 流式分析

    • Flow cytometric analysis of Mouse CD36 expression on mouse peritoneal exudates cells. Mouse peritoneal exudates cells were stained with SDT FITC Rat Anti-Mouse F4/80 Antibody (S0B5113) at 5 μl/test and either Alexa Fluor® 647 Armenian Hamster IgG Isotype Control (Left panel) or SDT Alexa Fluor® 647 Armenian Hamster Anti-Mouse CD36 Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.