PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Hu, Ms |
RRBP1, also known as ribosome-binding protein 1, is a membrane-bound protein located in the endoplasmic reticulum (ER) and is critical for ribosome binding. It plays a role in ER proliferation, secretory pathways, and secretory cell differentiation, as well as mediating ER-microtubule interactions. Alternative splicing of RRBP1 results in protein isoforms with different ribosome-binding affinities and secretory functions. This protein is also implicated in various cancers, such as oral squamous cell carcinoma, cervical squamous cell carcinoma, and colorectal cancer, where its expression is often associated with disease progression and prognosis. Recent studies have shown that RRBP1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking. Additionally, it has been identified as a novel peroxisomal biogenesis factor in human cells.
WB result of RRBP1 Rabbit pAb
Primary antibody: RRBP1 Rabbit pAb at 1/1000 dilution
Lane 1: HepG2 whole cell lysate 20 µg
Lane 2: Caco-2 whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 152 kDa
Observed MW: 100-140 kDa
WB result of RRBP1 Rabbit pAb
Primary antibody: RRBP1 Rabbit pAb at 1/1000 dilution
Lane 1: NIH/3T3 whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 152 kDa
Observed MW: 100-120 kDa
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